Instrumentation Development
Rapid product development reaps well-known rewards: accelerated time to market and lower development cost. Successful Figure 1: Example of a common IVD instrument architecture using a heated wheel of cuvettes with a reagent dispenser at a fixed position. The incubation wheel can hold up to 15 cuvettes. Each cuvette passes out of the incubation wheel block when its duration time has expired. The sample generator creates items (cuvettes) that flow through the model. Cuvettes are...
Recently developed rapid tests provide significant improvements that increase the scope and reliability of these tests. The trend toward rapid tests that enable quantitative interpretation through an objective measurement creates market demand for Figure 1. After an assay-specific method is completed, the accompanying file is downloaded to the reader. the development of corresponding reader systems and accompanying software. At the same time, rapid test manufacturers usually have...
  Shopping for parts, components, services, and new technologies at the Clinical Lab Expo next week? You're in luck. Here's just a tiny sampling of what will be on display there. Isolation Miniature Valves Solenoid-operated valves use a flexible diaphragm to isolate the solenoid actuation mechanism from the fluid path. When the valve is energized, the solenoid retracts an armature that is attached to a flexible diaphragm. In a normally closed valve, this raises the diaphragm, allowing...
The Clinical Lab Expo will feature new science and technology in every area of clinical diagnostics, automation, information systems, point of care, OEM, and biotech. Roughly 750 organizations will occupy about 2000 booths. According to Clinical Lab Expo's Website, "You will see more products in every clinical lab discipline than at any other show." Find What You Need The Clinical Lab Expo will have special sections for special products. Visit the special sections for point-of-...
Many of the world’s greatest inventions have often drawn inspiration from other diverse industries. For example, two-dimensional color flow Doppler imaging, a major breakthrough in cardiac diagnostics, came about through military radar engineers teaming up with Japanese physicians. The Coulter Counter, which revolutionized hematology by enabling the counting of blood cells, was invented as a result of technical experience gained through exposure to a number of global industries....
Gen-Probe's Panther system Developing an amplified molecular instrument is challenging. It is a time-consuming and costly endeavor for manufacturers, and the end result must be a highly reliable, robust instrument. Add in the regulatory hurdles and issues related to marketing the product worldwide, and the task seems almost insurmountable. To learn more about how such challenges are overcome and why the benefits of developing such instruments are worth the costs, IVD Technology editor...
Blood is the only fluid that flows throughout the entire human body. Blood analysis can detect a wide range of common physiological problems such as anemia, diabetes, autoimmune deficiencies, infections, and cancers. It can also expose genetic information, viruses, organ deficiencies, etc. Hematology is the study of blood cells. Hematology analyzer instruments can take the form of a relatively simple handheld unit, a more sophisticated point-of-care diagnostic instrument, or a highly complex...
Thermo Scientific Nunc Immobilizer Streptavidin and Nunc Immobilizer Amino surfaces. The stability of all components in an IVD kit reflects its ability to maintain consistent, and therefore accurate, performance over time. Unlike commonly measured attributes, stability is problematic to assess prior to experimental use, and as such, there is a great onus on IVD manufacturers to ensure that any stability claims are substantiated. In today’s culture of mass manufacturing, extending...
When designing an IVD or other medical instrument, most engineers look at the requirements as a group of mechanical, fluidic, electrical and software systems interacting to produce a desired result. Often, these engineers see only part of the picture. Quite a few factors come into play both during design and manufacturing and after the instrument is deployed. Following the design phase is integrating systems, performing validation, gaining approvals, manufacturing, and servicing in the field....
Healthcare is being reshaped by IT. Some of the most influential solutions transforming the healthcare industry involve the flow of data, be it life-saving information transmitted to hard-to-reach locations following a natural disaster, or the aggregation of patient results on a single screen to accelerate actionable decision-making. The clinical laboratory environment is a relative newcomer to the widespread adoption of more sophisticated IT solutions compared to other segments of the...