A small, semiautomated nephelometer, together with Freelite serum-free light-chain assays, can be used in diagnosis, prognosis, and monitoring of patients with monoclonal gammopathies. The exclusive combination of Freelite and Mininephplus enables laboratories with small Freelite workloads to provide results for this essential assay quickly and easily. A comprehensive range of specialist protein assays includes –IgG, IgA, IgM, IgG1 –IgG4, rheumatoid factor, C reactive protein, C3, C4, albumin, apolipoprotein A1 and B, α-1 antitrypsin, β2microglobulin, anti-streptolysin O, caeruloplasmin, haptoglobin, microalbumin, prealbumin, transferrin, IgG-low level (RUO), and C1 inactivator (RUO). The Mininephplus is easy to use, with simple on-screen instructions in several languages and assay-specific magnetic swipe cards containing preprogrammed calibration curves. Its automatic assay blanking and reagent mixing ensures consistent results, and the preprogrammed, integrated, single-button pipette improves precision. An optional handheld sample barcode scanner and automatic calculation of sample results give users confidence in the accuracy the analyzer.